NPDC focuses on discovery of active therapeutic agents from Malaysia’s mega biodiversity natural resources. Research on local plants (My Nature 50,000), microorganisms and metabolites are actively conducted with the aim to isolate as much chemical compounds with potential therapeutic property as possible for the biopharmaceutical industry. Currently, extraction and isolation of natural products are focused on finding therapeutic agents with anti-aging, skin whitening, anti-inflammation, anti-viral, anti-microbial and anti-fungal activities.
In addition, research on Development of Herbal Products is also conducted with aim to address health problems in local community. Herbal remedies have become more popular nowadays as an alternative to conventional drugs and medicine mainly due to the lesser-known side effects compared to the chemical pharmaceutics. In this study, local herbs from Malay, Indian and Chinese traditional medicine will be extracted and formulated as an alternative treatment for diabetes. In vitro and in vivo study will also be conducted to evaluate toxicity anti-diabetic efficacy of the product formulated. NPDC also focuses on drug discovery using in silico methods. Computer-aided drug design is an important tool in drug discovery studies as it provides in-depth understanding of the molecular basis of drugs’ actions and allows exploration of chemical interactions betweendrugs and their receptors. The application of simulated drug design and computational analysis are strategised with an aim of discovering new potential chemical entities from natural resources. Hits obtained from the simulations are further characterised with laboratory work which includes plant extractions